Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes
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چکیده
منابع مشابه
Topical Administration of Somatostatin Prevents Retinal Neurodegeneration in Experimental Diabetes
Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Somatostatin (SST) is an endogenous neuroprotective peptide that is downregulated in the diabetic eye. The aim of the study was to test the usefulness of topical administration of SST in preventing retinal neurodegeneration. For this purpose, rats with streptozotocin-induced diabetes mellitus (STZ-DM) ...
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Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Since glucagon-like peptide 1 (GLP-1) exerts neuroprotective effects in the central nervous system and the retina is ontogenically a brain-derived tissue, the aims of the current study were as follows: 1) to examine the expression and content of GLP-1 receptor (GLP-1R) in human and db/db mice retinas; ...
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Objective-This study aimed to investigate the effect of topical administration of lint bells oil (LBOC) on wound contraction as well as healing process. Design- Experimental study. Animals- in order to follow-up current study, 60 Male Swiss albino mice were used. Procedures- Animals were randomly divided into 5 groups (NO=12) including; vehicle-recived negative control, pure oil-received and ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms19113578